Chlorpromazine
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Scientific Name
Chlorpromazine
Description of the Drug
Chlorpromazine is a phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00477
http://www.drugbank.ca/drugs/DB00477
Brand Name(s)
Elmarin, Largactil, Megaphen, Thorazine
Company Owner(s)
Glaxosmithkline, Watson Laboratories Inc, Abbott Laboratories Pharmaceutical Products Div, Kv Pharmaceutical Co, Actavis Mid Atlantic Llc, Genus Lifesciences Inc, Purepac Pharmaceutical Co, Ivax Pharmaceuticals Inc Sub Teva Pharmaceuticals Usa, Enaltec Labs Inc, Fosun Pharma Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| D2-like dopamine receptor | PROTEIN FAMILY | ANTAGONIST | CHEMBL2331075 |
| Serotonin 2a (5-HT2a) receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL224 |
Clinical Trial(s)
Unichem Links
| Atlas | chlorpromazine | |||||||||
| SureChEMBL | SCHEMBL8321 | |||||||||
| PharmGKB | PA448964 | |||||||||
| Human Metabolome Database | HMDB0014620 | |||||||||
| DrugBank | DB00477 | |||||||||
| PubChem: Thomson Pharma | 14923746 | |||||||||
| PubChem | 2726 | |||||||||
| Mcule | MCULE-5976054678 | |||||||||
| LINCS | LSM-4017 | |||||||||
| Nikkaji | J2.794D | |||||||||
| PDBe | Z80 | |||||||||
| BindingDB | 50001888 | |||||||||
| EPA CompTox Dashboard | DTXSID0022808 | |||||||||
| DrugCentral | 621 | |||||||||
| Brenda | 162818 | 229267 | 6497 | 113197 | 75626 | 145046 | 74854 | 145960 | 229268 | 727 |
| ChemicalBook | CB5547531 | |||||||||
| Guide to Pharmacology | 83 | |||||||||
| rxnorm | CHLORPROMAZINE HYDROCHLORIDE | CHLORPROMAZINE | ||||||||
| PubChem: Drugs of the Future | 12014508 | |||||||||
| KEGG Ligand | C06906 | |||||||||
| ChEBI | 3647 | |||||||||
| ZINC | ZINC000000044027 |
