Chlorothiazide
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Scientific Name
Chlorothiazide
Description of the Drug
Chlorothiazide is a thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00880
http://www.drugbank.ca/drugs/DB00880
Brand Name(s)
Chlorothiazide, Diuril, Saluric
Company Owner(s)
Fresenius Kabi Usa Llc, Lederle Laboratories Div American Cyanamid Co, Salix Pharmaceuticals Inc, Sagent Pharmaceuticals Inc, Hikma International Pharmaceuticals Llc, Sandoz Inc, Sun Pharmaceutical Industries Ltd, Hikma Pharmaceuticals Llc, Par Pharmaceutical Inc, Abc Holding Corp
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Thiazide-sensitive sodium-chloride cotransporter | SINGLE PROTEIN | INHIBITOR | CHEMBL1876 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL22329 | ||
| PharmGKB | PA448953 | ||
| Human Metabolome Database | HMDB0015018 | ||
| DrugBank | DB00880 | ||
| PubChem: Thomson Pharma | 15023005 | ||
| PubChem | 2720 | ||
| Mcule | MCULE-3497410863 | ||
| LINCS | LSM-5942 | ||
| Nikkaji | J2.807J | ||
| BindingDB | 39351 | ||
| EPA CompTox Dashboard | DTXSID0022800 | ||
| DrugCentral | 609 | ||
| Brenda | 96277 | ||
| ChemicalBook | CB6756754 | ||
| Guide to Pharmacology | 4835 | ||
| rxnorm | DIURIL | CHLOROTHIAZIDE SODIUM | CHLOROTHIAZIDE |
| PubChem: Drugs of the Future | 24714733 | ||
| KEGG Ligand | C07461 | ||
| ChEBI | 3640 | ||
| ZINC | ZINC000003872055 |
