Chlorhexidine

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Scientific Name: Chlorhexidine
Brand Name: Betasept, Hibiclens, Instillagel, Nupro Chlorhexidine, Oris, Oro-Clense, Paroex, Perichlor, Peridex, Periochip, Periogard, Prevora, X-pur
Company Owner: Xttrium laboratories inc, Sage products inc, Actavis mid atlantic llc, Hi tech pharmacal co inc, John o butler co, Novex pharma, Teva pharmaceuticals usa inc, Wockhardt eu operations (swiss) ag, 3m co, Colgate oral pharmaceuticals inc, Soapco inc, Ecolab inc, Regent medical americas llc, Johnson and johnson medical inc, Matrix medical corp, Kw griffen co, Becton dickinson and co, Kendall co, Becton dickinson surgical system, Molnlycke health care, Pharmaseal div baxter healthcare corp, Dexcel pharma technologies ltd
Mechanism Of Action Chlorhexidine’s broad-spectrum antimicrobial effects are due to its ability to disrupt microbial cell membranes. The positively charged chlorhexidine molecule reacts with negatively charged phosphate groups on microbial cell surfaces – this reaction both destroys the integrity of the cell, allowing leakage of intracellular material, and allows chlorhexidine to enter the cell, causing precipitation of cytoplasmic components and ultimately cell death.
Description of the Drug: Chlorhexidine is an antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00878