Chlordiazepoxide

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Scientific Name: Chlordiazepoxide
Brand Name: Chlorax, Librax
Company Owner: Valeant pharmaceuticals international, Abbott laboratories pharmaceutical products div, Rachelle laboratories inc, Ascot hosp pharmaceuticals inc div travenol laboratories inc, Barr laboratories inc, John j ferrante, Halsey drug co inc, Impax laboratories inc, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Lederle laboratories div american cyanamid co, Mm mast and co, Mylan pharmaceuticals inc, Parke davis div warner lambert co, Pioneer pharmaceuticals inc, Purepac pharmaceutical co, Roxane laboratories inc, Sandoz inc, Superpharm corp, Teva pharmaceuticals usa inc, Usl pharma inc, Vangard laboratories inc div midway medical co, Watson laboratories inc, West ward pharmaceutical corp, Alra laboratories inc
Mechanism Of Action Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) binding sites on GABA (A) receptor complexes at several sites within the central nervous system, including the limbic system and reticular formation. This results in an increased binding of the inhibitory neurotransmitter GABA to the GABA(A) receptor. BZDs, therefore, enhance GABA-mediated chloride influx through GABA receptor channels, causing membrane hyperpolarization. The net neuro-inhibitory effects result in the observed sedative, hypnotic, anxiolytic, and muscle relaxant properties.
Description of the Drug: Chlordiazepoxide is a benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00475