Chenodeoxycholic acid

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Scientific Name: Chenodeoxycholic acid
Brand Name: Chenodal
Company Owner: Not Available
Mechanism Of Action Chenodiol suppresses hepatic synthesis of both cholesterol and cholic acid, gradually replacing the latter and its metabolite, deoxycholic acid in an expanded bile acid pool. These actions contribute to biliary cholesterol desaturation and gradual dissolution of radiolucent cholesterol gallstones in the presence of a gall-bladder visualized by oral cholecystography. Bile acids may also bind the the bile acid receptor (FXR) which regulates the synthesis and transport of bile acids.
Description of the Drug: Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB06777