Carglumic Acid
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Scientific Name
Carglumic Acid
Description of the Drug
Carglumic acid is an analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06775
http://www.drugbank.ca/drugs/DB06775
Brand Name(s)
Carbaglu
Company Owner(s)
Novitium Pharma Llc, Navinta Llc, Recordati Rare Diseases Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Carbamoyl-phosphate synthase [ammonia], mitochondrial | SINGLE PROTEIN | POSITIVE ALLOSTERIC MODULATOR | CHEMBL2362990 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL373546 | |||||
| PharmGKB | PA165958402 | |||||
| Human Metabolome Database | HMDB0015673 | |||||
| DrugBank | DB06775 | |||||
| PubChem: Thomson Pharma | 15042291 | |||||
| PubChem | 121396 | |||||
| Mcule | MCULE-6817913906 | |||||
| LINCS | LSM-45453 | |||||
| Nikkaji | J2.088.972A | |||||
| EPA CompTox Dashboard | DTXSID7046706 | |||||
| DrugCentral | 3068 | |||||
| Brenda | 49247 | 94283 | 182128 | 108761 | 44500 | 44501 |
| ChemicalBook | CB6183743 | |||||
| Guide to Pharmacology | 7458 | |||||
| rxnorm | CARBAGLU | CARGLUMIC ACID | ||||
| KEGG Ligand | C05829 | |||||
| ChEBI | 71028 | |||||
| ZINC | ZINC000001530283 |
