Canagliflozin
Back to search| Scientific Name: | Canagliflozin |
| Brand Name: | Invokamet, Invokana |
| Company Owner: | Not Available |
| Mechanism Of Action | The sodium-glucose co-transporter2 (SGLT2) , is found in the proximal tubules of the kidney, and reabsorbs filtered glucose from the renal tubular lumen. Canagliflozin inhibits the SGLT2 co-transporter. This inhibition leads to lower reabsorption of filtered glucose into the body and decreases the renal threshold for glucose (RTG) , leading to increased glucose excretion in the urine |
| Description of the Drug: | Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM) . Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. |
| Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB08907
