Back to search
Scientific Name: Canagliflozin
Brand Name: Invokamet, Invokana
Company Owner: Not Available
Mechanism Of Action The sodium-glucose co-transporter2 (SGLT2) , is found in the proximal tubules of the kidney, and reabsorbs filtered glucose from the renal tubular lumen. Canagliflozin inhibits the SGLT2 co-transporter. This inhibition leads to lower reabsorption of filtered glucose into the body and decreases the renal threshold for glucose (RTG) , leading to increased glucose excretion in the urine
Description of the Drug: Canagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM) . Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from