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Scientific Name: Calfactant
Brand Name: Infasurf
Company Owner: Not Available
Mechanism Of Action Pulmonary surfactant is an endogenous substance produced in the lungs that functions to decrease surface tension at the air: fluid interface on the alveolar surface. In premature infants with pulmonary surfactant deficiency, surface tension can increase to the point where sections of lung collapse and respiratory distress syndrome (RDS) develops. Calfactant adsorbs rapidly to the surface of the alveolar air: fluid interface and modifies surface tension to a minimum of less than 3 mN/m. It acts in a manner similar to natural lung surfactant, thus preventing or treating respiratory distress syndrome.
Description of the Drug: Calfactant is a lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from