Calcitriol
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Scientific Name
Calcitriol
Description of the Drug
Calcitriol is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00136
http://www.drugbank.ca/drugs/DB00136
Brand Name(s)
Calcijex, Calcitriol, Dihydroxycholecalciferol, Dihydroxyvitamin D 3, Rocaltrol, Silkis, Topitriol, Vectical
Company Owner(s)
Fresenius Medical Care North America, American Regent Inc, Validus Pharmaceuticals Llc, Abbvie Inc, Bionpharma Inc, Akorn Operating Co Llc, Teva Pharmaceuticals Usa Inc, Fresenius Kabi Usa Llc, Hospira Inc, Amneal Pharmaceuticals
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Vitamin D receptor | SINGLE PROTEIN | AGONIST | CHEMBL1977 |
Clinical Trial(s)
Unichem Links
| Atlas | 1alpha,25-Dihydroxyvitamin D3 | 1,25-dihydroxyvitamin D3 | ||||||||
| SureChEMBL | SCHEMBL3245 | |||||||||
| Human Metabolome Database | HMDB0001903 | |||||||||
| DrugBank | DB00136 | |||||||||
| PubChem: Thomson Pharma | 14758022 | 14855739 | ||||||||
| PubChem | 5280453 | |||||||||
| NMRShiftDB | 60020500 | |||||||||
| LINCS | LSM-43088 | |||||||||
| Nikkaji | J17.427K | |||||||||
| PDBe | VDX | |||||||||
| BindingDB | 50200182 | |||||||||
| EPA CompTox Dashboard | DTXSID5022722 | |||||||||
| LipidMaps | LMST03020258 | |||||||||
| DrugCentral | 466 | |||||||||
| Metabolights | MTBLC17823 | |||||||||
| Brenda | 84138 | 199247 | 12463 | 168065 | 102023 | 86868 | 163402 | 156164 | 1953 | 168069 |
| Rhea | 17823 | |||||||||
| Guide to Pharmacology | 2779 | |||||||||
| SwissLipids | SLM:000000475 | |||||||||
| rxnorm | ROCALTROL | CALCITRIOL | VECTICAL | |||||||
| PubChem: Drugs of the Future | 12012574 | |||||||||
| KEGG Ligand | C01673 | |||||||||
| ChEBI | 17823 | |||||||||
| ZINC | ZINC000100015048 |
