Cabozantinib

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Molecule Structure

Scientific Name

Cabozantinib

Description of the Drug

Cabozantinib is a tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB08875

Brand Name(s)

Cabometyx, Cometriq

Company Owner(s)

Exelixis Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Hepatocyte growth factor receptor SINGLE PROTEIN INHIBITOR CHEMBL3717
Vascular endothelial growth factor receptor 2 SINGLE PROTEIN INHIBITOR CHEMBL279

Unichem Links

SureChEMBL SCHEMBL360795
Human Metabolome Database HMDB0249524
DrugBank DB08875
PubChem 25102847
LINCS LSM-1195
Nikkaji J3.085.595G
BindingDB 50021574
EPA CompTox Dashboard DTXSID10233968
DrugCentral 4715
Brenda 213439
Guide to Pharmacology 5887
rxnorm CABOMETYX CABOZANTINIB S-MALATE CABOZANTINIB COMETRIQ
ChEBI 72317
ZINC ZINC000070466416