Scientific Name: Buserelin
Brand Name: Suprefact
Company Owner: Not Available
Mechanism Of Action Buserelin stimulates the pituitary gland’s gonadotrophin-releasing hormone receptor (GnRHR) . Buserelin desensitizes the GnRH receptor, reducing the amount of gonadotropin. In males, this results in a reduction in the synthesis and release of testosterone. In females, estrogen secretion is inhibited. While initially, there is a rise in FSH and LH levels, chronic administration of Buserelin results in a sustained suppression of these hormones.
Description of the Drug: Buserelin is a LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females.
Protein Data Bank: Not Available
Source: DrugBank Online – Retrieved 2023-01-23 from