Buserelin
Back to searchScientific Name: | Buserelin |
Brand Name: | Suprefact |
Company Owner: | Not Available |
Mechanism Of Action | Buserelin stimulates the pituitary gland’s gonadotrophin-releasing hormone receptor (GnRHR) . Buserelin desensitizes the GnRH receptor, reducing the amount of gonadotropin. In males, this results in a reduction in the synthesis and release of testosterone. In females, estrogen secretion is inhibited. While initially, there is a rise in FSH and LH levels, chronic administration of Buserelin results in a sustained suppression of these hormones. |
Description of the Drug: | Buserelin is a LHRH agonist used for the palliative treatment of hormone-dependent advanced carcinoma of the prostate gland in males and treatment of endometriosis in females. |
Protein Data Bank: | Not Available |
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB06719