Scientific Name: Bupropion
Brand Name: Aplenzin, Auvelity, Budeprion, Contrave, Forfivo, Wellbutrin, Zyban
Company Owner: Not Available
Mechanism Of Action Bupropion is a norepinephrine/dopamine-reuptake inhibitor (NDRI) that exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake of the neurotransmitters norepinephrine and dopamine from the synaptic cleft, therefore prolonging their duration of action within the neuronal synapse and the downstream effects of these neurotransmitters. More specifically, bupropion binds to the norepinephrine transporter (NET) and the dopamine transporter (DAT) .
Description of the Drug: Bupropion is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD) , seasonal affective disorder (SAD) , and as an aid to smoking cessation.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB01156