Molecule Structure

Scientific Name

Bupropion

Description of the Drug

Bupropion is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01156

Brand Name(s)

Not Available

Company Owner(s)

Glaxosmithkline, Jubilant Generics Ltd, Invagen Pharmaceuticals Inc, Watson Laboratories Inc, Anchen Pharmaceuticals Inc, Yichang Humanwell Pharmaceutical Co Ltd, Granules Pharmaceuticals Inc, Nalpropion Pharmaceuticals Llc, Mylan Pharmaceuticals Inc, Impax Laboratories Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Dopamine transporter SINGLE PROTEIN INHIBITOR CHEMBL238
Norepinephrine transporter SINGLE PROTEIN INHIBITOR CHEMBL222

Unichem Links

SureChEMBL SCHEMBL38777
PharmGKB PA448687
Human Metabolome Database HMDB0001510
DrugBank DB01156
PubChem: Thomson Pharma 15196401
PubChem 444
LINCS LSM-1267
Nikkaji J283.224K
BindingDB 50048392
EPA CompTox Dashboard DTXSID7022706
DrugCentral 435
Brenda 19651
ChemicalBook CB7202445
Guide to Pharmacology 7135
rxnorm BUPROPION HYDROCHLORIDE WELLBUTRIN BUPROPION APLENZIN ZYBAN BUPROPION HYDROBROMIDE
KEGG Ligand C06860
ChEBI 3219