Back to search
Scientific Name: Buprenorphine
Brand Name: Belbuca, Buprenex, Buprenorphine, Butrans, Probuphine, Sublocade, Suboxone, Subutex, Zubsolv
Company Owner: Purdue pharma lp, Reckitt benckiser pharmaceuticals inc, Bedford laboratories div ben venue laboratories inc, Hospira inc, Pharmaforce inc, Barr laboratories inc, Roxane laboratories inc
Mechanism Of Action Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. It demonstrates a high affinity for the mu-opioid receptor but has lower intrinsic activity compared to other full mu-opioid agonists such as
Description of the Drug: Buprenorphine is a partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
Protein Data Bank: Not Available
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00921