Bumetanide

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Molecule Structure

Scientific Name

Bumetanide

Description of the Drug

Bumetanide is a sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00887

Brand Name(s)

Betinex, Bumetanide, Bumex, Burinex, Lixil

Company Owner(s)

Amneal Pharmaceuticals Co Gmbh, Msn Laboratories Private Ltd, Sandoz Inc, West-Ward Pharmaceuticals International Ltd, Hospira Inc, Gland Pharma Ltd, Teva Parenteral Medicines Inc, Validus Pharmaceuticals Llc, Upsher Smith Laboratories Llc, Zydus Pharmaceuticals Usa Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Sodium-(potassium)-chloride cotransporter 2 SINGLE PROTEIN INHIBITOR CHEMBL1874

Unichem Links

SureChEMBL SCHEMBL27525
PharmGKB PA448682
Human Metabolome Database HMDB0015024
DrugBank DB00887
PubChem: Thomson Pharma 14852701
PubChem 2471
Mcule MCULE-6802013568
LINCS LSM-2848
Nikkaji J3.168B
PDBe 82U
BindingDB 25903
EPA CompTox Dashboard DTXSID5022699
DrugCentral 427
Brenda 151916
ChemicalBook CB9382992
Guide to Pharmacology 4837
rxnorm BUMETANIDE BUMEX
ChEBI 3213
ZINC ZINC000003813061