Bumetanide
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Scientific Name
Bumetanide
Description of the Drug
Bumetanide is a sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00887
http://www.drugbank.ca/drugs/DB00887
Brand Name(s)
Betinex, Bumetanide, Bumex, Burinex, Lixil
Company Owner(s)
Amneal Pharmaceuticals Co Gmbh, Msn Laboratories Private Ltd, Sandoz Inc, West-Ward Pharmaceuticals International Ltd, Hospira Inc, Gland Pharma Ltd, Teva Parenteral Medicines Inc, Validus Pharmaceuticals Llc, Upsher Smith Laboratories Llc, Zydus Pharmaceuticals Usa Inc
Mechanism(s) Of Action
Target Name | Target Type | Action Type | Target ChEMBL ID |
---|---|---|---|
Sodium-(potassium)-chloride cotransporter 2 | SINGLE PROTEIN | INHIBITOR | CHEMBL1874 |
Clinical Trial(s)
Unichem Links
SureChEMBL | SCHEMBL27525 | |
PharmGKB | PA448682 | |
Human Metabolome Database | HMDB0015024 | |
DrugBank | DB00887 | |
PubChem: Thomson Pharma | 14852701 | |
PubChem | 2471 | |
Mcule | MCULE-6802013568 | |
LINCS | LSM-2848 | |
Nikkaji | J3.168B | |
PDBe | 82U | |
BindingDB | 25903 | |
EPA CompTox Dashboard | DTXSID5022699 | |
DrugCentral | 427 | |
Brenda | 151916 | |
ChemicalBook | CB9382992 | |
Guide to Pharmacology | 4837 | |
rxnorm | BUMETANIDE | BUMEX |
ChEBI | 3213 | |
ZINC | ZINC000003813061 |