Bosentan
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Scientific Name
Bosentan
Description of the Drug
Bosentan is a dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00559
http://www.drugbank.ca/drugs/DB00559
Brand Name(s)
Tracleer
Company Owner(s)
Amneal Pharmaceuticals Co Gmbh, Alembic Pharmaceuticals Ltd, Sun Pharmaceutical Industries Ltd, Par Pharmaceutical Inc, Watson Laboratories Inc, Natco Pharma Ltd, Alvogen Pine Brook Inc, Mylan Pharmaceuticals Inc, Actelion Pharmaceuticals Us Inc, Zydus Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Endothelin receptor, ET-A/ET-B | PROTEIN FAMILY | ANTAGONIST | CHEMBL2096678 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL4218 | |||
| PharmGKB | PA10034 | |||
| Human Metabolome Database | HMDB0014699 | |||
| DrugBank | DB00559 | |||
| PubChem: Thomson Pharma | 14763764 | |||
| PubChem | 104865 | |||
| Mcule | MCULE-3074160312 | |||
| LINCS | LSM-5825 | |||
| Nikkaji | J594.472D | |||
| PDBe | K86 | |||
| BindingDB | 50061101 | |||
| EPA CompTox Dashboard | DTXSID7046627 | |||
| DrugCentral | 392 | |||
| ChemicalBook | CB3425624 | |||
| Guide to Pharmacology | 3494 | |||
| rxnorm | TRACLEER | BOSENTAN | BOSENTAN MONOHYDRATE | BOSENTAN ANHYDROUS |
| PubChem: Drugs of the Future | 12014838 | |||
| ChEBI | 51450 | |||
| ZINC | ZINC000001538857 |
