| Scientific Name: |
Bortezomib |
| Brand Name: |
Velcade |
| Company Owner: |
Millennium pharmaceuticals inc |
| Mechanism Of Action |
The ubiquitin-proteasome pathway is a homeostatic proteolytic pathway for intracellular protein degradation: proteins marked with a poly-ubiquitin chain are degraded to small peptides and free ubiquitin by the proteasome, which is a large multimeric protease. |
| Description of the Drug: |
Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
| Protein Data Bank: |
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