Back to search
Scientific Name: Bortezomib
Brand Name: Velcade
Company Owner: Millennium pharmaceuticals inc
Mechanism Of Action The ubiquitin-proteasome pathway is a homeostatic proteolytic pathway for intracellular protein degradation: proteins marked with a poly-ubiquitin chain are degraded to small peptides and free ubiquitin by the proteasome, which is a large multimeric protease.
Description of the Drug: Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from