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Scientific Name: Bazedoxifene
Brand Name: Duavee, Duavive
Company Owner: Not Available
Mechanism Of Action Bazedoxifene belongs to a class of compounds known as selective estrogen receptor modulators (SERMs) . Bazedoxifene acts as both an oestrogen-receptor agonist and/or antagonist, depending upon the cell and tissue type and target genes. Bazedoxifene decreases bone resorption and reduces biochemical markers of bone turnover to the premenopausal range. These effects on bone remodelling lead to an increase in bone mineral density (BMD) , which in turn contributes to a reduction in the risk of fractures. Bazedoxifene functions primarily as an oestrogen-receptor antagonist in uterine and breast tissues.
Description of the Drug: Bazedoxifene is a selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from