Azathioprine
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Scientific Name
Azathioprine
Description of the Drug
Azathioprine is an immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn’s disease, and ulcerative colitis.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00993
http://www.drugbank.ca/drugs/DB00993
Brand Name(s)
Azamune, Azapress, Azasan, Azathioprine, Berkaprine, Immunoprin 50, Imuran, Kentaprine, Oprisine 50
Company Owner(s)
Alkem Laboratories Ltd, Zydus Pharmaceuticals Usa Inc, Casper Pharma Llc, Aaipharma Llc, Amneal Pharmaceuticals Llc, Sebela Ireland Ltd, Hikma Pharmaceuticals Usa Inc, Rising Pharma Holdings Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Amidophosphoribosyltransferase | SINGLE PROTEIN | INHIBITOR | CHEMBL2362992 |
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
Clinical Trial(s)
Unichem Links
| Atlas | azathioprine | |||
| SureChEMBL | SCHEMBL4278 | |||
| PharmGKB | PA448515 | |||
| Human Metabolome Database | HMDB0015128 | |||
| DrugBank | DB00993 | |||
| PubChem: Thomson Pharma | 15222101 | 14775167 | 14824335 | |
| PubChem | 2265 | |||
| Mcule | MCULE-8637589610 | |||
| LINCS | LSM-42936 | |||
| BindingDB | 50373919 | |||
| EPA CompTox Dashboard | DTXSID4020119 | |||
| DrugCentral | 269 | |||
| Brenda | 4790 | |||
| ChemicalBook | CB2170327 | |||
| Guide to Pharmacology | 7120 | |||
| rxnorm | AZATHIOPRINE | IMURAN | AZATHIOPRINE SODIUM | AZASAN |
| KEGG Ligand | C06837 | |||
| ChEBI | 2948 | |||
| ZINC | ZINC000004258316 |
