Azacitidine
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Scientific Name
Azacitidine
Description of the Drug
Azacitidine is a pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00928
http://www.drugbank.ca/drugs/DB00928
Brand Name(s)
Azacitidine, Onureg, Vidaza
Company Owner(s)
Cipla Ltd, Celgene Corp, Natco Pharma Ltd, Shilpa Medicare Ltd, Actavis Llc, Accord Healthcare Inc, Dr Reddys Laboratories Ltd, Meitheal Pharmaceuticals Inc, Lupin Ltd, Amneal Eu Ltd
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| RNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311222 |
| DNA (cytosine-5)-methyltransferase 1 | SINGLE PROTEIN | INHIBITOR | CHEMBL1993 |
| DNA | NUCLEIC-ACID | INHIBITOR | CHEMBL2311221 |
| DNA (cytosine-5)-methyltransferase 3A | SINGLE PROTEIN | INHIBITOR | CHEMBL1992 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL3741 | |
| PharmGKB | PA451996 | |
| Human Metabolome Database | HMDB0015063 | |
| DrugBank | DB00928 | |
| PubChem: Thomson Pharma | 14749656 | 15019893 |
| PubChem | 9444 | |
| Mcule | MCULE-8318770472 | |
| NMRShiftDB | 20209750 | |
| LINCS | LSM-5218 | |
| Nikkaji | J1.523G | |
| PDBe | 5AE | |
| BindingDB | 50424715 | |
| EPA CompTox Dashboard | DTXSID9020116 | |
| DrugCentral | 25 | |
| Guide to Pharmacology | 6796 | |
| rxnorm | AZACITIDINE | VIDAZA |
| PubChem: Drugs of the Future | 12013374 | |
| KEGG Ligand | C11262 | |
| ChEBI | 2038 | |
| ZINC | ZINC000003861768 |
