Aripiprazole
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Scientific Name
Aripiprazole
Description of the Drug
Aripiprazole is an atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette’s syndrome.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB01238
http://www.drugbank.ca/drugs/DB01238
Brand Name(s)
Abilify, Abilify maintena, Abilify maintena kit, Abilify mycite kit, Aripiprazole
Company Owner(s)
Alkem Laboratories Ltd, Macleods Pharmaceuticals Ltd, Otsuka Pharmaceutical Development And Commercialization Inc, Boscogen Inc, Mylan Pharmaceuticals Inc, Zydus Pharmaceuticals Usa Inc, Prinston Pharmaceutical Inc, Torrent Pharmaceuticals Ltd, Ajanta Pharma Ltd, Accord Healthcare Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Serotonin 1a (5-HT1a) receptor | SINGLE PROTEIN | PARTIAL AGONIST | CHEMBL214 |
| Dopamine D2 receptor | SINGLE PROTEIN | PARTIAL AGONIST | CHEMBL217 |
| Serotonin 2a (5-HT2a) receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL224 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL8255 | |
| PharmGKB | PA10026 | |
| Human Metabolome Database | HMDB0005042 | |
| DrugBank | DB01238 | |
| PubChem: Thomson Pharma | 14759758 | 15103350 |
| PubChem | 60795 | |
| Mcule | MCULE-4329329262 | |
| LINCS | LSM-5776 | |
| Nikkaji | J573.417G | |
| PDBe | 9SC | |
| BindingDB | 50130293 | |
| EPA CompTox Dashboard | DTXSID3046083 | |
| DrugCentral | 242 | |
| Metabolights | MTBLC31236 | |
| Brenda | 18292 | |
| ChemicalBook | CB42487193 | CB8210870 |
| Guide to Pharmacology | 34 | |
| rxnorm | ARIPIPRAZOLE | ABILIFY |
| PubChem: Drugs of the Future | 12014488 | |
| KEGG Ligand | C12564 | |
| ChEBI | 31236 | |
| ZINC | ZINC000001851149 |
