Aprepitant
Back to searchMolecule Structure
Scientific Name
Aprepitant
Description of the Drug
Aprepitant is a substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00673
http://www.drugbank.ca/drugs/DB00673
Brand Name(s)
Aprepitant, Cinvanti, Emend
Company Owner(s)
Sandoz Inc, Torrent Pharma Inc, Merck And Co Inc, Heron Therapeutics Inc, Glenmark Pharmaceuticals Sa Switzerland, Merck Sharp And Dohme Corp A Sub Of Merck And Co Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Neurokinin 1 receptor | SINGLE PROTEIN | ANTAGONIST | CHEMBL249 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL264924 | ||
| Human Metabolome Database | HMDB0014811 | ||
| DrugBank | DB00673 | ||
| PubChem: Thomson Pharma | 14787735 | 14812125 | 14861083 |
| PubChem | 135413536 | ||
| LINCS | LSM-5637 | ||
| Nikkaji | J1.059.639D | ||
| PDBe | GBQ | ||
| BindingDB | 50220136 | ||
| EPA CompTox Dashboard | DTXSID3049047 | ||
| DrugCentral | 230 | ||
| ChemicalBook | CB32557888 | CB7500857 | |
| Guide to Pharmacology | 3490 | ||
| rxnorm | EMEND | APREPITANT | CINVANTI |
| PubChem: Drugs of the Future | 12015114 | ||
| ChEBI | 499361 | ||
| ZINC | ZINC000027428713 |
