Ampicillin

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Scientific Name: Ampicillin
Brand Name: Unasyn
Company Owner: Acic fine chemicals inc, Apothecon inc div bristol myers squibb, Baxter healthcare corp anesthesia and critical care, Consolidated pharmaceutical group inc, Gc hanford manufacturing co, Istituto biochimico italiano spa, Instituto biochemico italiano spa, International medication systems ltd, Eli lilly and co, Marsam pharmaceuticals llc, Sandoz inc, Wyeth ayerst laboratories, Bristol laboratories inc div bristol myers co, Glaxosmithkline, Parke davis div warner lambert co, American antibiotics llc, Dava pharmaceuticals inc, Ivax pharmaceuticals inc sub teva pharmaceuticals usa, Lederle laboratories div american cyanamid co, Mylan pharmaceuticals inc, Purepac pharmaceutical co, Teva pharmaceuticals usa inc, Vitarine pharmaceuticals inc, Pfizer laboratories div pfizer inc, Bristol myers squibb co, Apothecon sub bristol myers squibb co
Mechanism Of Action By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, Ampicillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that Ampicillin interferes with an autolysin inhibitor.
Description of the Drug: Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00415