Amphotericin B

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Molecule Structure

Scientific Name

Amphotericin B

Description of the Drug

Amphotericin B is an antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00681

Brand Name(s)

Abelcet, Ambisome, Amophotericin B, Ampho-moronal, Amphotec, Amphotercin B, Amphotericin b, Amphotericine B, Amphotericitin B, Amphotreicin B, Ampotericin B, Fungilin, Fungilin in orabase, Fungizone

Company Owner(s)

Sun Pharma Industries Ltd, Bristol Myers Squibb Co, Apothecon Inc Div Bristol Myers Squibb, Abraxis Pharmaceutical Products, Astellas Pharma Us Inc, Teva Parenteral Medicines Inc, Xgen Pharmaceuticals Djb Inc, Abbott Laboratories, Leadiant Biosciences Inc, Alkopharma Usa Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Ergosterol SMALL MOLECULE SEQUESTERING AGENT CHEMBL2364028

Unichem Links

SureChEMBL SCHEMBL17973
PharmGKB PA448415
Human Metabolome Database HMDB0014819
DrugBank DB00681
PubChem: Thomson Pharma 14889787 14791931
PubChem 5280965 91819969
NMRShiftDB 60058697
BindingDB 50457967
EPA CompTox Dashboard DTXSID9022601
LipidMaps LMPK06000002
DrugCentral 197
Metabolights MTBLC2682
Brenda 240153 32851 50632 5518
ChemicalBook CB3425912
rxnorm AMPHOTERICIN B AMPHOTERICIN ABELCET AMPHOTERICIN B LIPID COMPLEX AMBISOME AMPHOTERICIN B LIPOSOMAL
PubChem: Drugs of the Future 12012606
KEGG Ligand C06573
ChEBI 2682
ZINC ZINC000253387843