Amoxapine
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Scientific Name
Amoxapine
Description of the Drug
Amoxapine is a tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00543
http://www.drugbank.ca/drugs/DB00543
Brand Name(s)
Amoxapine, Asendin, Asendis, Defanyl
Company Owner(s)
Lederle Laboratories Div American Cyanamid Co, Watson Laboratories Inc, Chartwell Rx Sciences Llc, Watson Pharmaceuticals Inc An Indirect Wholly Owned Sub Of Teva Pharmaceuticals Usa Inc
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Serotonin transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL228 |
| Dopamine receptor | PROTEIN FAMILY | ANTAGONIST | CHEMBL2096905 |
| Norepinephrine transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL222 |
Clinical Trial(s)
Unichem Links
| SureChEMBL | SCHEMBL33950 |
| PharmGKB | PA448405 |
| Human Metabolome Database | HMDB0014683 |
| DrugBank | DB00543 |
| PubChem: Thomson Pharma | 14950373 |
| PubChem | 2170 |
| Mcule | MCULE-9583761109 |
| LINCS | LSM-2021 |
| Nikkaji | J3.129A |
| BindingDB | 22870 |
| EPA CompTox Dashboard | DTXSID7022598 |
| DrugCentral | 191 |
| ChemicalBook | CB5375947 |
| Guide to Pharmacology | 201 |
| rxnorm | AMOXAPINE |
| PubChem: Drugs of the Future | 12013426 |
| ChEBI | 2675 |
| ZINC | ZINC000000000931 |
