Amodiaquine

Back to search
Scientific Name: Amodiaquine
Brand Name: Not Available
Company Owner: Parke davis div warner lambert co
Mechanism Of Action The mechanism of plasmodicidal action of amodiaquine is not completely certain. Like other quinoline derivatives, it is thought to inhibit heme polymerase activity. This results in accumulation of free heme, which is toxic to the parasites. The drug binds the free heme preventing the parasite from converting it to a form less toxic. This drug-heme complex is toxic and disrupts membrane function.
Description of the Drug: Amodiaquine is an antimalarial drug.
Protein Data Bank:
Source: DrugBank Online – DrugBank.com. Retrieved 2023-01-23 from https://go.drugbank.com/drugs/DB00613