Amitriptyline
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Scientific Name
Amitriptyline
Description of the Drug
Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00321
http://www.drugbank.ca/drugs/DB00321
Brand Name(s)
Not Available
Company Owner(s)
Centaur Pharmaceuticals Private Ltd, Schering Corp Sub Schering Plough Corp, Sun Pharmaceutical Industries Inc, New River Pharmaceuticals Inc, Watson Laboratories Inc, Copley Pharmaceutical Inc, Halsey Drug Co Inc, Mankind Pharma Ltd, Mylan Pharmaceuticals Inc, Purepac Pharmaceutical Co
Mechanism(s) Of Action
| Target Name | Target Type | Action Type | Target ChEMBL ID |
|---|---|---|---|
| Serotonin transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL228 |
| Norepinephrine transporter | SINGLE PROTEIN | INHIBITOR | CHEMBL222 |
Clinical Trial(s)
Unichem Links
| Atlas | amitriptyline | |||
| SureChEMBL | SCHEMBL7824 | |||
| PharmGKB | PA448385 | |||
| Human Metabolome Database | HMDB0014466 | |||
| DrugBank | DB00321 | |||
| PubChem: Thomson Pharma | 14775196 | |||
| PubChem | 2160 | |||
| Mcule | MCULE-3537115467 | |||
| LINCS | LSM-3190 | |||
| Nikkaji | J4.103C | |||
| PDBe | TP0 | |||
| BindingDB | 50020712 | |||
| EPA CompTox Dashboard | DTXSID7022594 | |||
| DrugCentral | 180 | |||
| Brenda | 24403 | 4978 | 211300 | |
| Guide to Pharmacology | 200 | |||
| rxnorm | LIMBITROL | AMITRIPTYLINE HYDROCHLORIDE | AMITRIPTYLINE | ELAVIL |
| KEGG Ligand | C06824 | |||
| ChEBI | 2666 | |||
| ZINC | ZINC000000968257 |
