Ambrisentan

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Molecule Structure

Scientific Name

Ambrisentan

Description of the Drug

Ambrisentan is a selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB06403

Brand Name(s)

Letairis, Volibris

Company Owner(s)

Apotex Inc, Cipla Ltd, Sigmapharm Laboratories Llc, Sun Pharmaceutical Industries Ltd, Par Pharmaceutical Inc, Watson Laboratories Inc, Aurobindo Pharma Ltd, Gilead Sciences Inc, Mylan Pharmaceuticals Inc, Zydus Pharmaceuticals Usa Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Endothelin receptor, ET-A/ET-B PROTEIN FAMILY ANTAGONIST CHEMBL2096678

Unichem Links

SureChEMBL SCHEMBL3679
DrugBank DB06403
PubChem: Thomson Pharma 14779987
PubChem 6918493
LINCS LSM-45789
Nikkaji J2.651.033C
BindingDB 50146710
EPA CompTox Dashboard DTXSID4046282
DrugCentral 4337
ChemicalBook CB71011125
Guide to Pharmacology 3951
rxnorm LETAIRIS AMBRISENTAN
PubChem: Drugs of the Future 12015371
ChEBI 135949
ZINC ZINC000000538627