Molecule Structure

Scientific Name

Alosetron

Description of the Drug

Alosetron is a 5-HT3 antagonist used to treat diarrhea-predominant IBS.

Source: DrugBank Online – DrugBank.com. Retrieved 2023-03-10 from
http://www.drugbank.ca/drugs/DB00969

Brand Name(s)

Not Available

Company Owner(s)

Eywa Pharma Pte Ltd, Par Pharmaceutical Inc, Mankind Pharma Ltd, Amneal Pharmaceuticals Of New York Llc, Sebela Ireland Ltd, Hikma Pharmaceuticals Usa Inc, Rising Pharma Holdings Inc

Mechanism(s) Of Action

Target Name Target Type Action Type Target ChEMBL ID
Serotonin 3a (5-HT3a) receptor SINGLE PROTEIN ANTAGONIST CHEMBL1899

Unichem Links

SureChEMBL SCHEMBL631
PharmGKB PA164745502
Human Metabolome Database HMDB0015104
DrugBank DB00969
PubChem: Thomson Pharma 14922649
PubChem 2099
LINCS LSM-5576
Nikkaji J532.750D
PDBe S7Y
BindingDB 50014558 93624
EPA CompTox Dashboard DTXSID6044278
DrugCentral 129
ChemicalBook CB8149787
Guide to Pharmacology 2296
rxnorm ALOSETRON LOTRONEX ALOSETRON HYDROCHLORIDE
ChEBI 253342
ZINC ZINC000013537284