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Scientific Name: Alfacalcidol
Brand Name: One-alpha
Company Owner: Not Available
Mechanism Of Action In conditions like chronic renal failure, renal bone disease, hypoparathyroidism, and vitamin D dependent rickets, the kidneys’ capacity for 1α-hydroxylation is impaired, leading to reduced production of endogenous 1, 25-dihydroxyvitamin D and aberrated mineral metabolism. As an active and potent analog of vitamin D, alfacalcidol works to restore the functions and activities of endogenous 1, 25-dihydroxyvitamin D.
Description of the Drug: Alfacalcidol is a vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia.
Protein Data Bank:
Source: DrugBank Online – Retrieved 2023-01-23 from